Managing Protein-Energy Wasting: The Role of Serum Albumin in Stratifying Risk in Dialysis Patients

Activity Overview

Serum albumin is an important way to monitor patients in stages 4 and 5 chronic kidney disease and there is evidence it is being underutilized. At the same time, there is increasing evidence that serum albumin is more accurate than realized in predicting malnutrition and cardiovascular disease. As serum albumin declines, risk of sudden death or other adverse outcomes increases. The role of inflammation in this process is being seen as equally important to nutrition. This program outlines the recommendations of KDOQI guidelines as well as the new science behind using albumin as a way to stratify risk.

Accreditation

Physician

The National Kidney Foundation is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The National Kidney Foundation designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity is applicable for Category 2-B Credit through the American Osteopathic Association for Doctors of Osteopathy.

Physician Assistant

AAPA accepts certificates of participation for educational activities certified for Category I credit from AOACCME, Prescribed credit from AAFP, and AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society. Physician assistants may receive a maximum of 1.0 hour of Category I credit for completing this program.

Nurse and Technician

The National Kidney Foundation is an approved provider of continuing nursing education by the New York State Nurses Association, an accredited approver by the American Nurses Credentialing Center's Commission on Accreditation.

It has been assigned code 6EXQ7J-PRV-O6.

1.0 contact hour will be awarded.

Nurse Practitioner

This program has been approved for 1.0 contact hour of continuing education by the American Academy of Nurse Practitioners. Program ID 0902094.

This program was planned in accordance with AANP CE Standards and Policies and AANP Commercial Support Standards.

Dietitian

CPE

The National Kidney Foundation is a Continuing Professional Education (CPE) Accredited Provider with the Commission on Dietetic Registration (CDR). Registered dietitians (RDs) and dietetic technicians, registered (DTRs) will receive 1.0 continuing professional education unit (CPEU) for completion of this program/material.


Pharmacist

ACPE

The University of Illinois at Chicago, College of Pharmacy, is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. The ACPE universal activity number assigned to this educational offering is 016-999-09-023-H01-P.

This activity is accredited by the University of Illinois at Chicago, College of Pharmacy for 0.1 CEU (1.0 contact hour).

This activity is knowledge based.

Method of Participation

This activity contains two case studies, each of which has self-evaluation questions.

To complete the activity, you must follow each case study in its entirety and answer the questions. Once you have completed the activity, you will be directed to the Post Test and Evaluation to receive credit. The estimated time for completion is 1.0 hour.

Learning Objectives

  • Identify the factors contributing to poor outcomes in dialysis patients.

  • Recognize the clinical value of serum albumin in CKD patient assessment.

  • Describe patient outcomes associated with protein-energy wasting (PEW) and the rationale for monitoring adequate serum albumin levels based on scientific findings.

  • Identify recommended serum albumin targets according to current clinical practice guidelines and their value in predicting outcomes.

  • Discuss evolving concepts of PEW, malnutrition-inflammation syndrome and malnutrition-inflammation-atherosclerosis syndrome.


Release Date: May 15, 2009

Expiration Date: March 31, 2011

Faculty Disclosures

Joel D. Kopple, MD has been a Consultant, Speaker, Chair of the Advisory Board, and has received research support from Novo Nordisk.

Joel D. Kopple, MD Professor of Medicine and Public Health
David Geffen School of Medicine at UCLA and
UCLA School of Public Health
Division of Nephrology and Hypertension
Harbor-UCLA Medical Center
Long Beach, California

Kamyar Kalantar-Zadeh, MD, PhD, MPH has indicated that he has been an advisor for Novo Nordisk, a speaker for Nutripletion, and has participated in research with Abbott Nutrition.

Kamyar Kalantar-Zadeh, MD, PhD, MPH
Associate Professor of Medicine and Pediatrics
David Geffen School of Medicine
University of California, Los Angeles
Director, Dialysis Expansion Program and Epidemiology
Harbor-UCLA Medical Center
Los Angeles, California

Jerrilynn Burrowes, PhD, RD, CDN has disclosed that she has no financial relationships with any commercial entity producing health-care related products and/or services.

Jerrilynn Burrowes, PhD, RD, CDN
Associate Professor School of Health Professions and Nursing
Department of Nutrition
C.W.Post Campus
Long Island University
Brookville, New York

Planning Committee Disclosures

Genevieve Coorey, M.A. (Ed.), Renal Cert., BSN, RN has disclosed that she has no financial relationships with any commercial entity producing health-care related products and/or services.

Genevieve Coorey, M.A. (Ed.), Renal Cert., BSN, RN
Quality Assurance and Program Director
National Kidney Foundation
Kidney Learning System

Kathleen Falkenstein PhD, PNP-BC has disclosed that she has no financial relationships with any commercial entity producing health-care related products and/or services.

Kathleen Falkenstein, PhD, PNP-BC
Assistant Professor
Drexel University
Philadelphia, PA

Lois J. Hill, MS, RD, CSR, LD has disclosed that she has no financial relationships with any commercial entity producing health-care related products and/or services.

Lois Hill, MS, RD, CSR
Renal Nutritionist/Owner
Nutrition Solutions
Lexington, KY

Margaret MacDougall, MD, PhD has disclosed that she has no financial relationships with any commercial entity producing health-care related products and/or services.

Margaret MacDougall, MD, PhD
Clinical Professor, Medicine/Nephrology
SUNY Upstate Medical University
Syracuse, New York

Nancy Plese has disclosed that she has no financial relationships with any commercial entity producing health-care related products and/or services.

Nancy Plese
Program Director
National Kidney Foundation
Kidney Learning System

Lynda Szczech, MD has served on the Speaker’s Bureau and as a Consultant for Genzyme, FMC, GSK, and Gilead. She has received research support from Genzyme and Pfizer.

Lynda Szczech, MD, MSCE
Associate Professor
Duke University Medical Center
Durham, NC

Maria Taylor, PharmD, MSc has disclosed that she has no financial relationships with any commercial entity producing health-care related products and/or services.

Maria Taylor, PharmD, MSc
Senior Pharmacist-Nephrology
Preceptor University of Alabama at Birmingham
Birmingham, Alabama

Polly Gerber Zimmermann, RN, MS, MBA, CEN, FAEN has disclosed that she has no financial relationships with any commercial entity producing health-care related products and/or services.

Polly Zimmermann, RN, MS, MBA, CEN, FAEN
Assistant Professor
Harry Truman College
Chicago, Illinois

Contact Information

For any questions concerning this activity, please send an email to CMEinfo@kidney.org or call NKF at 1-800-622-9010.

To view NKF privacy and confidentiality policy as it relates to CME/CE activity, please visit http://www.kidney.org/

For additional information about KLS and/or to learn about KLS educational opportunities, contact NKF at 800-622-9010 or visit http://www.kidney.org/kls

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